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The role of amphetamine metabolism in the α-methyl-p-tyrosine—d-amphetamine catalepsy

✍ Scribed by A.C. Sayers; Sheila L. Handley

Book ID
118321268
Publisher
Elsevier Science
Year
1973
Tongue
English
Weight
286 KB
Volume
24
Category
Article
ISSN
0014-2999

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Catalepsy induced by α-methyl-p-tyrosine
Catalepsy induced by α-methyl-p-tyrosine andd-amphetamine: The rÔle of catecholamine metabolism
✍ A. C. Sayers; Sheila L. Handley 📂 Article 📅 1974 🏛 Springer 🌐 English ⚖ 580 KB

The effect of inhibition of monoamine oxidase (M\_AO), catechol-Omethyltransferase (COMT) and Dopa-decarboxylase on the catalepsy induced by d-amphetamine in ~-methyl-p-tyrosine (a-MpT) treated rats has been investigated. Administration of an MAO inhibitor concomitant with a-MpT slightly antagonize