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The role of adjuvant intra-arterial chemotherapy (IAC) after pancreatic resection for ductal carcinoma of the pancreas

✍ Scribed by Iacono, Calogero; Cantore, Maurizio; Pagani, Mauro; Bortolasi, Luca; Mambrini, Andrea; Zicari, Marianna; Miserocchi, Luigi; Acerbi, Anna; Smerieri, Franco; Serio, Giovanni

Book ID: 123592497
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 163 KB
Volume: 118
Category: Article
ISSN: 0016-5085
DOI: 10.1016/S0016-5085(00)81974-5

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## Abstract ## Background and Objectives p53 tumor suppressor gene has a dual role as a trigger of apoptosis and as an initiator of DNA repair. The Bcl‐2 can work to protect cells from apoptosis, which is induced by p53 gene. These facts suggest the significant role of these genes in the genesis a