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The role of accessory cells in polyclonal T cell activation. I. Both induction of interleukin 2 production and of interleukin 2 responsiveness by concanavalin A are accessory cell dependent

✍ Scribed by Thomas Hünig; Michael Loos; Anneliese Schimpl

Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
623 KB
Volume
13
Category
Article
ISSN
0014-2980

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Highly purified murine lymph node T cells were used to test the hypothesis that polyclonal T cell activation requires the recognition of mitogen-modified major histocompatibility complex (MHC) antigens on accessory cells (AC) by the T cells. A variety of tumor cells lines, including macrophage, B an