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The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME–Tox)

✍ Scribed by Gergely Szakács; András Váradi; Csilla Özvegy-Laczka; Balázs Sarkadi

Book ID
113568843
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
686 KB
Volume
13
Category
Article
ISSN
1359-6446

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1. The molecular and functional characterization of transport proteins is emerging rapidly and significant numbers of drugs have been shown to be substrates or inhibitors. The purpose of this review is to highlight the in vivo preclinical and clinical evidence that supports a role for transport prot