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The RNA binding protein, HuR, posttranscriptionally regulates the expression of chemokines and cytokines*1

✍ Scribed by ATASOY, U


Book ID
119274198
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
25 KB
Volume
113
Category
Article
ISSN
1097-6825

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## Abstract HuR is a ligand for nuclear mRNAs containing adenylate‐uridylate‐rich (ARE) elements in the 3′‐untranslated region. Once bound to the mRNA, HuR is recognized by adapter proteins that then facilitate nuclear export of the complex. In the cytosol, HuR is thought to function to control sta