The risk of medullary thyroid carcinoma in patients with Hirschsprung's disease
✍ Scribed by Richard Škába; Šárka Dvořáková; Eliška Václavíková; Petr Vlček; Miroslava Frantlová; Běla Bendlová
- Publisher
- Springer-Verlag
- Year
- 2006
- Tongue
- English
- Weight
- 126 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0179-0358
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Findings on pre-operative thyroid scintiscans in 29 patients with medullary carcinoma of the thyroid were compared with results of palpation and pathological findings. Six patients had a normal uptake of 131I or 99mTc in tumours 1.5--8 cm in diameter. When compared with 111 pre-operative scintiscans
## BACKGROUND. All patients with medullary carcinoma of the thyroid (MCT) diag-Ulla Bergholm, M
The multiple endocrine neoplasia type 2 (MEN2) syndromes and Hirschsprung's disease (HSCR) are inherited neurocristopathies characterized by medullary thyroid carcinoma (MTC), pheochromocytoma, parathyroid disease, and gastrointestinal neuromatosis. Mutations in the RET proto-oncogene are the underl