The risk of developing cervical cancer in Mexican women is associated to CYP1A1 MspI polymorphism
✍ Scribed by Teresa Juárez-Cedillo; Maite Vallejo; José Manuel Fragoso; Dulce Maria Hernández-Hernández; José Manuel Rodríguez-Pérez; Sergio Sánchez-García; María del Carmen García-Peña; Alejandro García-Carrancá; Alejandro Mohar-Betancourt; Julio Granados; Gilberto Vargas-Alarcón
- Book ID
- 116429319
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 155 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0959-8049
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📜 SIMILAR VOLUMES
## Background and objective There are inconsistent data of the cytochrome __P450 1A1__ (__CYP1A1__) Ile462Val (rs1048943) single nuclear polymorphism (SNP) as a genetic susceptibility factor for cervical cancer in various populations. Moreover, little is known about the interaction of this SNP with
## Abstract CYP1A1 is likely to play an important role in the etiology of CaP through its function in activating environmental procarcinogens and catalyzing the oxidative metabolites of estrogens. To test the hypothesis that genetic polymorphisms in the __CYP1A1__ gene may be associated with the ri