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The rise of nuclear and cytosolic Ca2+can be uncoupledin HeLa cells

✍ Scribed by Pauline P. Y. Lui; S. K. Kong; K. P. Fung; C. Y. Lee

Book ID
106111506
Publisher
Springer
Year
1998
Tongue
English
Weight
153 KB
Volume
436
Category
Article
ISSN
0031-6768

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✍ Velia Cardin; Ruth Lezama; M. Eugenia Torres-MΓ‘rquez; Herminia Pasantes-Morales πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 358 KB

## Abstract Hyposmolarity (βˆ’30%) in cultured cerebellar astrocytes raised cytosolic Ca^2+^ concentration ([Ca^2+^]~i~) from 160 to 400 nM and activated the osmosensitive taurine release (OTR) pathway. Although OTR is essentially [Ca^2+^]~i~‐independent, further increase in [Ca^2+^]~i~ by ionomycin