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The Ribozyme World

Book ID: 111681071
Publisher: American Association for the Advancement of Science
Year: 2011
Tongue: English
Weight: 261 KB
Volume: 332
Category: Article
ISSN: 0036-8075
DOI: 10.1126/science.332.6026.145-b

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The hammerhead ribozyme is an intriguing RNA molecule with the ability to serve as a catalyst to cleave sequence-specifically RNA molecules in an intermolecular reaction. Preferentially Mg 2ϩ is required for optimal activity by inducing the catalytically competent conformation and by possibly acting