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The Retinoblastoma Protein Binds the Promoter of the Survival Gene bcl-2 and Regulates Its Transcription in Epithelial Cells through Transcription Factor AP-2

✍ Scribed by Decary, S.; Decesse, J. T.; Ogryzko, V.; Reed, J. C.; Naguibneva, I.; Harel-Bellan, A.; Cremisi, C. E.


Book ID
125421757
Publisher
American Society for Microbiology
Year
2002
Tongue
English
Weight
505 KB
Volume
22
Category
Article
ISSN
0270-7306

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## Abstract The Runx2 factor is an essential component of the regulatory mechanisms that control transcription during skeletogenesis. Runx2/p57 expression in osteoblastic cells is controlled by the P1 promoter, which is recognized by key regulators of osteoblast differentiation including homeodomai