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πŸ“

The Retina and Circadian Rhythms

✍ Scribed by Gianluca Tosini Ph.D., Douglas G. McMahon Ph.D. (auth.), Gianluca Tosini, P. Michael Iuvone, Douglas G. McMahon, Shaun P. Collin (eds.)


Publisher
Springer-Verlag New York
Year
2014
Tongue
English
Leaves
245
Series
Springer Series in Vision Research 1
Edition
1
Category
Library

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✦ Synopsis


Daily rhythms are a ubiquitous feature of living systems. Generally, these rhythms are not just passive consequences of cyclic fluctuations in the environment, but instead originate within the organism. In mammals, including humans, the master pacemaker controlling 24-hour rhythms is localized in the suprachiasmatic nuclei of the hypothalamus (SCN). This circadian clock is responsible for the temporal organization of a wide variety of functions, ranging from sleep and food intake, to physiological measures such as body temperature, heart rate and hormone release. Moreover, accumulating evidence suggests that dysfunction of the circadian rhythms due to genetic mutations or environmental factors (i.e., jet-lag or shift work) contribute to the development of many pathologies, including sleep disorders, mood and affective disorders such as major depression, bipolar disorder and schizophrenia, as well as the risk of metabolic and cardiovascular disorders.

✦ Table of Contents


Front Matter....Pages i-viii
Introduction....Pages 1-2
Fundamental Retinal Circuitry for Circadian Rhythms....Pages 3-26
Circadian Photoreception: From Phototransduction to Behaviour....Pages 27-48
Role of Melatonin and Dopamine in the Regulation of Retinal Circadian Rhythms....Pages 49-68
Circadian Organization of the Vertebrate Retina....Pages 69-94
Rhythmicity of the Retinal Pigment Epithelium....Pages 95-112
Retinal Circadian Rhythms in Mammals Revealed Using Electroretinography....Pages 113-129
Circadian Effects on Retinal Light Damage....Pages 131-170
Circadian Rhythms and Vision in Zebrafish....Pages 171-193
Circadian Modulation of the Limulus Eye for Day and Night Vision....Pages 195-212
Molluskan Ocular Pacemakers: Lessons Learned....Pages 213-232
Back Matter....Pages 233-238

✦ Subjects


Neurosciences; Ophthalmology; Neurobiology


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