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The ret proto-oncogene induces apoptosis: Proapoptotic activity and hirschsprung disease

✍ Scribed by Christelle Forcet; Laure Granger; Véronique Corset; Marie-Claire Bordeaux; Dale E Bredesen; Marc Billaud; Patrick Edery; Patrick Mehlen


Book ID
114192180
Publisher
Portland Press
Year
1999
Tongue
English
Weight
192 KB
Volume
91
Category
Article
ISSN
0248-4900

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Germline mutations of the RET proto-oncogene have been found in familial and sporadic forms of Hirschsprung disease (HSCR), but also in the autosomal dominantly inherited multiple endocrine neoplasia type 2 (MEN2) syndromes, which comprise the medullary thyroid carcinoma (MTC) as an obligatory featu