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The RET proto-oncogene in human cancers

✍ Scribed by Jhiang, Sissy M

Book ID: 110064171
Publisher: Nature Publishing Group
Year: 2000
Tongue: English
Weight: 173 KB
Volume: 19
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1203857

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Missense germline mutations of the RET proto-oncogene have recently been identified in the hereditary cancer syndromes MENZA, MEN2B, and FMTC, all characterized by medullary carcinoma, hut also including phaeochromocytoma in MEN2A and MEN2B and parathyroid disease in MENZA. In addition, somatic RET