The responses of motoneurones to 5-hydroxytryptamine
β Scribed by Olwen Parry; M.H.T. Roberts
- Book ID
- 118954114
- Publisher
- Elsevier Science
- Year
- 1980
- Tongue
- English
- Weight
- 464 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0028-3908
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π SIMILAR VOLUMES
5-Hydroxytryptamine (5-HT) is present in nerve fibres descending from the brainstem Raphe nuclei to motoneurones and its release is thought to exert excitatory actions. 5-HT, applied from the outside, directly depolarizes spinal and cranial motoneurones in slices. This action of 5-HT is mediated, in
The effects of microiontophoretic 5-hydroxytryptamine (5-HT) on the firing rate of red nucleus (RN) neurons were studied in urethane-anesthetized rats. The background discharge rate of almost all the neurons tested (97%) was modified by 5-HT, and generally increased (89%). Responses were dose depend