𝔖 Bobbio Scriptorium
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The responses of motoneurones to 5-hydroxytryptamine

✍ Scribed by Olwen Parry; M.H.T. Roberts


Book ID
118954114
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
464 KB
Volume
19
Category
Article
ISSN
0028-3908

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5-Hydroxytryptamine (5-HT) is present in nerve fibres descending from the brainstem Raphe nuclei to motoneurones and its release is thought to exert excitatory actions. 5-HT, applied from the outside, directly depolarizes spinal and cranial motoneurones in slices. This action of 5-HT is mediated, in

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The effects of microiontophoretic 5-hydroxytryptamine (5-HT) on the firing rate of red nucleus (RN) neurons were studied in urethane-anesthetized rats. The background discharge rate of almost all the neurons tested (97%) was modified by 5-HT, and generally increased (89%). Responses were dose depend