The response of malignant hyperthermia sensitive pigs to vecuronium
β Scribed by Richards, D.L.S. ;McGrath, C.J. ;Clutton, R.E. ;Lee, J.C.
- Book ID
- 115205521
- Publisher
- Elsevier
- Year
- 1989
- Weight
- 573 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0950-7817
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## Abstract The currently favored theory of pathogenesis of malignant hyperthermia (MH) implicates an abnormality in skeletal muscle calcium ion transport. During a MH crisis a profound lactic acidosis occurs and in MHβsensitive individuals a delayed recovery of venous lactate has been previously n
Electromechanical properties of skeletal muscle were compared between malignant hyperthermia (MH)-susceptible and control pigs. These muscle properties were studied both in vivo and in vitro. The in vivo time interval from nerve stimulation to onset of mechanical tension was longer in muscle of pigs