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The requirement of Ras and Rap1 for the activation of ERKs by cAMP, PACAP, and KCl in cerebellar granule cells

✍ Scribed by Yutaro Obara; Angela M. Horgan; Philip J. S. Stork


Book ID
111179993
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
809 KB
Volume
101
Category
Article
ISSN
0022-3042

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Chronic stimulation of cerebellar granule cells with N-methyl-D-aspartate (NMDA) or KCI induces a specific activation of the enzymes directly involved in glutamate neurotransmitter synthesis. Phosphate-activated glutaminase (PAG) activity is enhanced in cultured granule neurons incubated with 150 pM