The renin–angiotensin system in a rat model of hepatic fibrosis: Evidence for a protective role of Angiotensin-(1–7)
✍ Scribed by Regina Maria Pereira; Robson Augusto Souza dos Santos; Mauro Martins Teixeira; Virginia Hora Rios Leite; Lincoln Paiva Costa; Filipi Leles da Costa Dias; Lucíola S. Barcelos; Guilherme Birchal Collares; Ana Cristina Simões e Silva
- Book ID
- 116651243
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 680 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0168-8278
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Farnesoid X receptor (FXR) is a bile acid-activated transcription factor that is a member of the nuclear hormone receptor superfamily. FXR-null mice exhibit a phenotype similar to Byler disease, an inherited cholestatic liver disorder. In the liver, activation of FXR induces transcription of transpo
It has been shown that the renin-angiotensin system (RAS) plays key roles in the development of fibrosis in numerous organs, including the liver. Other studies have suggested that the RAS also may play roles in diseases of chronic inflammation. However, whether the RAS also can mediate acute inflamm