✦ LIBER ✦
The Removal of S-Cysteine Protection by Means of 2-Pyridine Sulfenyl Chloride and the Subsequent Formation of Disulfide Bonds. Preliminary communication
✍ Scribed by José V. Castell; Aung Tun-Kyi
- Book ID
- 102252438
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- German
- Weight
- 246 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0018-019X
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
2‐Pyridine sulfenyl chloride (PS‐Cl) is a useful reagent for simultaneously deprotecting and activating the mercapto‐group of cysteine and of cysteine‐peptides preliminary to disufide‐bond formation. The S‐protecting groups that are amenable to this reaction include trityl, diphenylmethyl, acetamidomethyl, t‐butyl, and t‐butylsulfenyl.