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The removal of hepatitis B virus from factor VIII concentrates by fractionation on ethylene maleic anhydride polyelectrolyte

✍ Scribed by S. A. Galpin; P. Karayiannis; S. M. Middleton; H. C. Thomas


Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
301 KB
Volume
14
Category
Article
ISSN
0146-6615

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✦ Synopsis


Chromatography with a solid-phase polyelectrolyte based on ethylene maleic anhydride polyelectrolyte (EMA PE) has been shown to remove a large proportion of hepatitis B surface antigen (HBsAg), including hepatitis B virus (HBV) particles, from contaminated cryoprecipitate. This process may reduce the risk of transmission of HBV infection when factor VIII concentrates are administered.