The relevance of the IgG subclass of autoantibodies for blister induction in autoimmune bullous skin diseases
β Scribed by Cassian Sitaru; Sidonia Mihai; Detlef Zillikens
- Book ID
- 106078716
- Publisher
- Springer-Verlag
- Year
- 2007
- Tongue
- English
- Weight
- 438 KB
- Volume
- 299
- Category
- Article
- ISSN
- 0340-3696
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## Abstract Autoimmune diseases are characterized by the loss of tolerance toward selfβantigens and the induction of destructive immune responses leading to tissue damage. Most patients with autoimmune diseases are treated with immunosuppressive drugs that suppress the immune response in a nonβspec
The subepidermal immunobullous diseases bullous pemphigoid (BP), cicatricial pemphigoid (CP), pemphigoid gestationis (PG) and linear IgA disease (LAD) are characterized by circulating and in vivo deposition of antibodies to antigens in the cutaneous basement membrane zone (BMZ). Indirect immunofluor