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The Relevance of Mean Corpuscular Volume of Heterozygotes to Prenatal Diagnosis of β-Thalassemia

✍ Scribed by D. RUND; D. FILON; E. A. RACHMILEWITZ; A. OPPENHEIM

Book ID: 119864583
Publisher: John Wiley and Sons
Year: 1990
Tongue: English
Weight: 116 KB
Volume: 612
Category: Article
ISSN: 0890-6564
DOI: 10.1111/j.1749-6632.1990.tb24348.x

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## Abstract β‐Thalassemia is the most common genetic disorder in the Lebanese population. Of the 200 different mutations in the β‐globin gene that leads to thalassemia, the IVSI‐110 (29.87%), IVSI‐6 (20.74%), IVSI‐1 (14.07%), IVSII‐1 (9.13%), Cd29 (9.13%), and Cd30 (3.95%) mutations are the most fr