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The release of oxytocin, vasopressin and associated neurophysins after electroconvulsive therapy

✍ Scribed by Allan I. F. Scott; P. Anne Shering; Stafford L. Lightman; Jean-Jacques Legros; Lawrence J. Whalley

Publisher: John Wiley and Sons
Year: 1991
Tongue: English
Weight: 244 KB
Volume: 6
Category: Article
ISSN: 0885-6222
DOI: 10.1002/hup.470060211

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Blood concentrations of oxytocin (OT), vasopressin (VP) and their associated neurophysins were measured before and after the first electroconvulsive therapy (ECT) given to 12 depressed patients. The maximum concentrations of all four peptides coincided at +2 min, but the increases in OT and VP were about four‐fold greater than their associated neurophysins. None of the peptide increases correlated with spike‐wave or total cerebral seizure activity as measured by electroencephalogram.

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