The relative frequency of subgroup I and II rotaviruses in black infants in South Africa
✍ Scribed by A. D. Steele; J. J. Alexander
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 462 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0146-6615
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✦ Synopsis
stool specimens were collected from bIack South African infants and young children with acute gastroenteritis, and tested for the presence of rotavirus. Monoclonal antibodies against the major inner capsid protein were used in an enzyme linked immunosorbent assay to determine the subgroup specificity of the rotavirus isolates. Subgroup I1 rotaviruses occurred more frequently than subgroup I isolates (74.4% vs 12.3%), while 13.3% could not be typed and may indicate the presence of a third subgroup. Two of the subgroup I isolates had a Iong RNA profile (ie, faster moving gene segment 11) typical of the subgroup I1 human rotaviruses, and a single subgroup I1 strain had a short RNA profile possibly indicating an in vivo rotavirus reassortant.