The Relationships Between the Degree of β-Isomerization of Type I Collagen Degradation Products in the Urine and Aging, Menopause and Osteoporosis with Fractures

Measurement of urinary excretion of noni

Measurement of urinary excretion of nonisomerized and β-isomerized forms of type I collagen breakdown products to monitor the effects of the bisphosphonate zoledronate in Paget's disease

✍ Patrick Garnero; Evelyne Gineyts; A. Victoria Schaffer; John Seaman; Pierre D. D 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 680 KB

## Objective: We have previously shown that the woven pagetic bone in patients with paget's disease is characterized by an impaired degree of beta-isomerization of c-telopeptides of type i collagen molecules, which results in a preferential urinary excretion of nonisomerized type i collagen c-telop