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The Relationship of MHC-Peptide Binding and T Cell Activation Probed Using Chemically Defined MHC Class II Oligomers

✍ Scribed by Jennifer R Cochran; Thomas O Cameron; Lawrence J Stern

Book ID
117722606
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
262 KB
Volume
12
Category
Article
ISSN
1074-7613

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## Abstract MHC class II‐peptide multimers are a valuable tool for antigen‐specific detection of CD4^+^ T cells. However, it has been proposed that T cells in a hypo‐responsive state can have diminished binding of such multimers. In the present study, we investigated this phenomenon at the clonal l