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The relationship between uracil incorporation into DNA and the expression of fragile sites in human chromosomes

✍ Scribed by Hagerman, Paul J.

Publisher: John Wiley and Sons
Year: 1984
Tongue: English
Weight: 193 KB
Volume: 19
Category: Article
ISSN: 0148-7299
DOI: 10.1002/ajmg.1320190227

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## Abstract ## Objective To investigate whether the abnormal expression of matrix metalloproteinases (MMPs) 3, 9, and 13 and ADAMTS‐4 by human osteoarthritic (OA) chondrocytes is associated with epigenetic “unsilencing.” ## Methods Cartilage was obtained from the femoral heads of 16 patients wit