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The relationship between peptide structure and antibacterial activity

✍ Scribed by Jon-Paul S Powers; Robert E.W Hancock

Book ID
116830258
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
195 KB
Volume
24
Category
Article
ISSN
0196-9781

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## Abstract A series of Trp and Arg analogs of antibacterial indolicidin (Ind) was synthesized and the antimicrobial and hemolytic activities were investigated. [L^9^]Ind, [L^11^]Ind, [K^8^,L^9^]Ind and [K^6, 8^,L^9^]Ind showed desirable characteristics, exhibiting negligible hemolytic activity whi