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The relationship between clinically confirmed cobalamin deficiency and serum methylmalonic acid

✍ Scribed by Dr. L. MOELBY; K. RASMUSSEN; M. K. JENSEN; K. O. PEDERSEN


Book ID
114741941
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
407 KB
Volume
228
Category
Article
ISSN
0954-6820

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The serum cobalamin assay is the primary diagnostic test for cobalamin deficiency. It appears to be an excellent screening test since most patients with clinically confirmed cobalamin deficiency have low levels. Recent studies indicate that the clinical picture of cobalamin deficiency is much more d

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We compared the sensitivity and specificity of the two metabolite tests, methylmalonic acid (MMA) and total homocysteine (Hcy) in serum, and serum cobalamin (Cbl) in patients referred to our hospital because of suspected cobalamin deficiency and a serum cobalamin value at the referring unit <200 pmo