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The relationship between bcl-2 expression and response to chemotherapy in acute leukaemia

✍ Scribed by Z. T. Maung; F. R. MacLean; M. M. Reid; A. D. J. Pearson; S. J. Proctor; P. J. Hamilton; A. G. Hall

Book ID: 114713773
Publisher: John Wiley and Sons
Year: 1994
Tongue: English
Weight: 411 KB
Volume: 88
Category: Article
ISSN: 0007-1048
DOI: 10.1111/j.1365-2141.1994.tb04984.x

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## Background and objectives: Telomerase is thought to be responsible for cell immortality, and bcl-2 has been demonstrated to regulate apoptosis. recent studies have shown a wide occurrence of telomerase activation and bcl-2 deregulation in human carcinoma cells. ## Methods: We examined telomera