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The relation between hypoxia-inducible factor (HIF)-1α and HIF-2α expression with anemia and outcome in surgically treated head and neck cancer

✍ Scribed by Stuart C. Winter; Ketan A. Shah; Cheng Han; Leticia Campo; Helen Turley; Russell Leek; Rogan J. Corbridge; Graham J. Cox; Adrian L. Harris


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
295 KB
Volume
107
Category
Article
ISSN
0008-543X

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## Abstract Her‐2/__neu__ (__erb__B‐2) oncogene overexpression is associated with increased tumor progression and metastasis. Fatty acid synthase (FAS), the key lipogenic enzyme responsible for the endogenous synthesis of fatty acids, has been shown to be one of the genes regulated by Her‐2/__neu__