The ‘regulatory’ β-subunit of protein kinase CK2 negatively influences p53-mediated allosteric effects on Chk2 activation

Inducible expression of the regulatory p

Inducible expression of the regulatory protein kinase CK2β subunit: Incorporation into complexes with catalytic CK2 subunits and re-examination of the effects of CK2β on cell proliferation

✍ Greg Vilk; D. Richard Derksen; Dr. David W. Litchfield 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 357 KB

## Abstract The regulatory subunit of protein kinase CK2, designated CK2β, exists both free in cells and in complexes with the CK2 catalytic subunits. Growing evidence suggests that CK2β has functions dependent and independent of the CK2 catalytic subunits. There have been indications that CK2β has