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The regulation of urea amidolyase ofSaccharomyces cerevisiae

โœ Scribed by Yves Lemoine; Evelyne Dubois; Jean-Marie Wiame

Book ID
104693112
Publisher
Springer
Year
1978
Tongue
English
Weight
672 KB
Volume
166
Category
Article
ISSN
1617-4615

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โœฆ Synopsis

Constitutivity for the synthesis of the urea amidolyase bienzymatic complex is obtained by durOh mutations located in the regulatory genetic region adjacent to the dur1, dur2 gene cluster. The durOh mutations act only in cis and are a new case of cis effect strongly cancelled in alpha/a diploid, similar to cargA+Oh mutation shown previously to lead to arginase constitutivity. Illegitimate diploids do not show such a cancellation of constitutivity. The constitutivity produced by durOh mutation comprises the process of induction and the release of the glutamine effect. It does not impair the NH+4 effect.

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