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The regulation of pro-inflammatory gene expression induced by pigment epithelium-derived factor in rat cultured microglial cells

โœ Scribed by Tomomi Sanagi; Takeshi Yabe; Haruki Yamada

Book ID
116767537
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
200 KB
Volume
380
Category
Article
ISSN
0304-3940

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Pigment epithelium-derived factor (PEDF) is a potent and broadly acting neurotrophic factor that protects neurons in various types of cultured neurons against glutamate excitotoxicity and induced-apoptosis. Some of the effects of PEDF reflect specific changes in gene expression, mediated via activat