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The regulation of M1 muscarinic acetylcholine receptor desensitization by synaptic activity in cultured hippocampal neurons

✍ Scribed by Jonathon M. Willets; Carl P. Nelson; Stefan R. Nahorski; R. A. John Challiss


Book ID
111180469
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
519 KB
Volume
103
Category
Article
ISSN
0022-3042

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We investigated the role of kainate (KA) receptor activation and desensitization in inducing the increase in the intracellular free Ca(2+) concentration ([Ca(2+)](i)) in individual cultured rat hippocampal neurons. The rat hippocampal neurons in the cultures were shown to express kainate receptor su