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The regulation of hippocampal LTP by the molecular switch, a form of metaplasticity, requires mGlu5 receptors

✍ Scribed by Zuner A. Bortolotto; Valerie J. Collett; Francois Conquet; Zhengping Jia; Herman van der Putten; Graham L. Collingridge


Book ID
116784394
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
702 KB
Volume
49
Category
Article
ISSN
0028-3908

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Low-frequency stimulation induces a new
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Low frequency-induced short-term synaptic plasticity was investigated in hippocampal slices with 60-electrode recording array. Remarkably, the application of low-frequency stimulation (1 Hz) for a short duration (3-5 min) resulted in the induction of a slow-onset longterm potentiation (LTP) in the i