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The regulation of growth and protein expression by estrogen in vitro: A study of 8 human ovarian carcinoma cell lines

✍ Scribed by Langdon, S.P.; Hirst, G.L.; Miller, E.P.; Hawkins, R.A.; Tesdale, A.L.; Smyth, J.F.; Miller, W.R.

Book ID
123362135
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
484 KB
Volume
50
Category
Article
ISSN
0960-0760

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## Abstract The effects of EGF and TGF‐β1 on the proliferation of 2 ovarian carcinoma cell lines (IGROV1 and OVCCR1) were evaluated. The cell lines were adapted to grow in a restricted serum (0.5%) medium. EGF was required for proliferation of both ovarian cell lines. Low doses of TGF‐β1 inhibited