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The regulation of glycine transporter GLYT1 is mainly mediated by protein kinase Cα in C6 glioma cells

✍ Scribed by Norimitsu Morioka; Joynal Md. Abdin; Katsuya Morita; Tomoya Kitayama; Yoshihiro Nakata; Toshihiro Dohi

Book ID
116765196
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
567 KB
Volume
53
Category
Article
ISSN
0197-0186

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## Abstract Cultures of rat C6 rat glioma cells exhibit a diminished response to isoproterenol and forskolin after being treated with phorbol 12,13‐dibutyrate (PDbU). An IC50 for PDbU of 38±5 nM and 62±8 nM was observed in the isoproternol and forskolin response, respectively. Similarly, C6 culture