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The regulation of expression of endothelial leukocyte adhesion molecules as a regulatory step in atherosclerosis and inflammation

✍ Scribed by Raffaele De Caterina


Book ID
117575831
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
138 KB
Volume
50
Category
Article
ISSN
0753-3322

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InΒ―ammatory cytokines such as interleukin-1 (IL-1) and tumour necrosis factor-alpha (TNF-a), as well as shear stress, cause endothelial cells (ECs), to undergo not only functional alterations but also structural reorganizations, which contribute to vascular leakage. Like ECs of the human aorta, ECs