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The regulation of AβPP expression by RNA-binding proteins

✍ Scribed by Cara J. Westmark; James S. Malter

Book ID
118416634
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
638 KB
Volume
11
Category
Article
ISSN
1872-9649

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## Abstract HuR is a ligand for nuclear mRNAs containing adenylate‐uridylate‐rich (ARE) elements in the 3′‐untranslated region. Once bound to the mRNA, HuR is recognized by adapter proteins that then facilitate nuclear export of the complex. In the cytosol, HuR is thought to function to control sta