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The regulation of alpha chemokines during HIV-1 infection and leukocyte activation: relevance for HIV-1-associated dementia

✍ Scribed by Larisa Poluektova; Tim Moran; Marina Zelivyanskaya; Susan Swindells; Howard E Gendelman; Yuri Persidsky

Book ID
114137475
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
328 KB
Volume
120
Category
Article
ISSN
0165-5728

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## Abstract Limited drug penetration is an obstacle that is often encountered in the treatment of CNS diseases including human immunodeficiency virus type‐1 (HIV‐1) encephalitis (HIVE). One mechanism that may contribute to this phenomenon is the expression of ATP‐binding cassette (ABC) drug efflux