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The regulation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumor promotion by estradiol in female A/J mice

✍ Scribed by Wang, Ying-Jan; Chen, Rong-Jane; Chang, Louis W.; Ho, Yuan-Soon; Wu, Chih-Hsiung; Lin, Pinpin


Book ID
122699011
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
69 KB
Volume
221
Category
Article
ISSN
0378-4274

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## Abstract The promotional effects of butylated hydroxytoluene (BHT) on lung tumorigenesis induced by 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanone (NNK) was evaluated in a two‐stage model of lung tumorigenesis in the A/J mouse. Mice were treated in two separate experiments with 1.54 mmol/kg (9.1