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The regulation mechanism of c-jun and junB by human papillomavirus type 16 E5 oncoprotein

✍ Scribed by S. -L. Chen; C. -H. Huang; T. -C. Tsai; K. -Y. Lu; Y. -P. Tsao

Publisher
Springer Vienna
Year
1996
Tongue
English
Weight
905 KB
Volume
141
Category
Article
ISSN
1432-8798

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## Abstract The E5 oncoprotein of human papillomavirus type 16 downregulates surface MHC Class I and interacts with the heavy chain of the MHC complex __via__ the first hydrophobic domain, believed to form the first helical transmembrane region (TM1) of E5. TM1 contains 4 equally spaced di‐leucine