✦ LIBER ✦
The regulated expression of Epstein-Barr virus: evidence that the transition from primary to secondary protein synthesis in Raji cells superinfected with Epstein-Barr virus requires the synthesis of new RNA
✍ Scribed by G. J. Bayliss; H. Wolf
- Publisher
- Springer-Verlag
- Year
- 1987
- Tongue
- English
- Weight
- 426 KB
- Volume
- 176
- Category
- Article
- ISSN
- 0300-8584
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✦ Synopsis
In the presence of canavanine and the absence of arginine, superinfected Raji cells synthesize a limited spectrum of proteins (primary proteins). After the removal of canavanine at 8 h post infection, the cells proceed after a lag phase of 2-3 h to synthesize a second group of proteins. The appearance of these proteins can be prevented by addition of actinomycin-D to the chase media, suggesting that active primary proteins are required for the synthesis of new mRNA coding for the secondary proteins.