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The Reductive Half-reaction of Xanthine Oxidase. REACTION WITH ALDEHYDE SUBSTRATES AND IDENTIFICATION OF THE CATALYTICALLY LABILE OXYGEN

โœ Scribed by Xia, M.


Book ID
115448544
Publisher
The American Society for Biochemistry and Molecular Biology
Year
1999
Tongue
English
Weight
246 KB
Volume
274
Category
Article
ISSN
0021-9258

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โœ Karl Jug; Heiko Gerwens ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 697 KB

A quantum-chemical model for electrostatic effects (QCMEE) in biomolecules is applied to the reductive half-reaction of glucose oxidase. The electrostatic influence of the enzyme on its active center is estimated. Six different states of protonation of the active center are compared by a hybrid meth