✦ LIBER ✦
The Reductive Conversion of Some Cyclic and Acyclic vic-Epoxides to Alcohols by Means of Lithium Aluminium Hydride/Aluminium Trichloride
✍ Scribed by Vladimir Andrejević; Mira Bjelaković; Milan M. Mihailović; Mihailo Lj. Mihailović
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- German
- Weight
- 172 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0018-019X
No coin nor oath required. For personal study only.
✦ Synopsis
Unsubstituted medium-ring 1,2-epoxycycloalkanes and certain vie-epoxyalkanes are reduced to the corresponding alcohols very slowly when LiAIH, alone is used as reducing agent. However, the combination of LiA1H4 and AICI,, in a 2:l molar ratio (with respect to 1 mol-equiv. of epoxide) used in refluxing Et,O, greatly enhances these reductions, rendering them of interest for practical purposes.