The reduction of α,β-unsaturated nitriles and α-halonitriles with sodium hydrogen telluride
✍ Scribed by Gonzalo Blay; Luz Cardona; Begoña García; Luisa Lahoz; JoséR. Pedro
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 313 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0040-4020
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Activated nickel, produced by the ultrasound-promoted reduction of nickel iodide with lithium, catalyzes the 1,4 addition of phenylsilane to ct, 13-unsaturated ketones and ct, 13 -unsaturated nitriles to give, after hydrolysis, high yields of the products of 1, 2 hydrogenation.
## Abstract Treatment of 3‐methylamino‐5‐phenylthiophene with α,β‐unsaturated esters, __i.e.__, methyl acrylate, (__E__)‐methyl crotonate, diethyl fumarate, diethyl maleate and ethyl propiolate, in tetrahydrofuran for several days at reflux gave 1‐methyl‐3,4‐dihydrothieno[2,3‐__e__]pyridin‐2‐ones *