The reduction of N-phenylsulfonyl)indoles with sodium cyanoborohydride in trifluoroacetic acid

✍ Scribed by Daniel M. Ketcha; Brett A. Lieurance

• Book ID: 104244479
• Publisher: Elsevier Science
• Year: 1989
• Tongue: French
• Weight: 237 KB
• Volume: 30
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)93364-7

✦ Synopsis

The reduction of N-(phenylsulfonyl)inles to the corresponding N-(pknylsulfonyl)indolines can be accomplished with good to excellent yields using sodium cyanoborohydride (NaCNBH3) in triifluoroacetic acid (TFA).