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The recombinant kringle domain of urokinase plasminogen activator inhibits in vivo malignant glioma growth

โœ Scribed by Chung Kwon Kim; Sung Hee Hong; Young Ae Joe; Byoung-Shik Shim; Suk-Keun Lee; Yong-Kil Hong


Book ID
108583800
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
329 KB
Volume
98
Category
Article
ISSN
1347-9032

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Human malignant gliomas are highly vascularized and aggressive tumors. Angiogenesis inhibitors have been shown to induce regression of a variety of primary and metastatic tumors in vivo. However, their usefulness in treating brain tumors is not well understood. Angiostatin, a multiple kringle (1-4 o