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The receptor for human urokinase: a potential target for anti-invasive and anti-metastatic therapy

โœ Scribed by Maria Teresa Masucci; Francesco Blasi


Book ID
119037914
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
741 KB
Volume
57
Category
Article
ISSN
0049-3848

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Antisense oligodeoxynucleotides for urok
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## Abstract We have targeted the urokinaseโ€type plasminogen activator receptor (uPAR) with phosphorothioate antisense oligonucleotides (aODN) __in vitro__ to evaluate the antiโ€invasive and antiโ€proliferative effects of uPAR downโ€regulation, as well as __in vivo__ to evaluate antiโ€tumor and antiโ€met