The recent evolutionary origin of the phenylalanine-sensitive isozyme of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase in the enteric lineage of bacteria
✍ Scribed by Suhail Ahmad; John L. Johnson; Roy A. Jensen
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 791 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0022-2844
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## Abstract In __Escherichia coli__, the phenylalanine‐sensitive 3‐deoxy‐D‐arabino‐heptulosonate‐7‐phosphate synthase (DAHPS) AroG catalyzes the first committed step in the biosynthesis of aromatic compounds. To investigate the feedback inhibition site of AroG, mutated enzymes prepared with sequenc
## Abstract The first regulatory step in the synthesis of aromatic amino acids is catalyzed by 3‐deoxy‐D‐arabino‐heptulosonate 7‐phosphate synthase (DAHPS). In Escherichia coli, the allosteric DAHPS exists as three isozymes, AroG, AroF and AroH, each independently feedback‐inhibited by correspondin